Taq Polymerase

What is Taq Polymerase?

Taq DNA Polymerase is an thermostable DNA polymerase that catalyzes dNTPs into DNA, is frequently used in polymerase chain reaction (PCR). The name comes from thermophilic bacteriumThermus aquaticus

Why don't we basic Taq Polymerase?

Taq polymerase has many limitation such as low replication fidelity. They lack a 3' to 5' exonuclease proofreading activities with error rate 1/9,000. Standard Taq used in most lab still require time to optimise their PCR reaction, which can be tedious and time consuming. Therefore there are many modification made to improve basic Taq Polymerase for simplify, speed up and better performance. 

Ref: link1, link2, link3